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Article

Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction.

The Journal of cell biology - 19 Mar 2012

Ryan Scott D, Bhanot Kunal, Ferrier Andrew, De Repentigny Yves, Chu Alphonse, Blais Alexandre, Kothary Rashmi

Abstract excerpt

Loss of function of dystonin cytoskeletal linker proteins causes neurodegeneration in dystonia musculorum (dt) mutant mice. Although much investigation has focused on understanding dt pathology, the diverse cellular functions of dystonin isoforms remain poorly characterized. In this paper, we highlight novel functions of the dystonin-a2 isoform in mediating microtubule (MT) stability, Golgi organization, and flux...

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Identifiers

PMID: 22412020
DOI: 10.1083/jcb.201107096
PMCID: PMC3308695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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