Article
The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1.
Nature genetics - 1 Jul 1995
Brown A, Bernier G, Mathieu M, Rossant J, Kothary R
Abstract excerpt
Dystonia musculorum (dt) is a hereditary neurodegenerative disease in mice that leads to a sensory ataxia. We describe cloning of a candidate dt gene, dystonin, that is predominantly expressed in the dorsal root ganglia and other sites of neurodegeneration in dt mice. Dystonin encodes an N-termin...
Topics
- Amino Acid Sequence
- Animals
- Autoantigens
- Base Sequence
- Carrier Proteins
- Collagen
- Cytoskeletal Proteins
- DNA, Complementary
- Dystonia Musculorum Deformans
- Dystonin
- Gene Expression
- Humans
- In Situ Hybridization
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins