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Article

Gamete-specific DNA fragmentation in unfertilized human oocytes after intracytoplasmic sperm injection

1 Mar 1998

Abstract excerpt

The objective of the present study was to assess the integrity of maternal and/or paternal chromatin in injected oocytes that remained unfertilized after intracytoplasmic sperm injection (ICSI). The study was performed on 102 oocytes that failed to show pronuclear formation 18-20 h after ICSI. We used chromatin labelling with 4,6-diamidino-2-phenylindole (DAPI) to identify maternal and paternal chromatin, coupled...

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PMID: 9572438
DOI: 10.1093/humrep/13.3.703

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