Article
Suppression of the lethal effect of acidic-phospholipid deficiency in Escherichia coli by Bacillus subtilis chromosomal locus ypoP.
Bioscience, biotechnology, and biochemistry - 1 Mar 1998
Inoue K, Kishimoto A, Suzuki M, Matsuzaki H, Matsumoto K, Shibuya I
Abstract excerpt
An acidic-phospholipid deficiency caused by the pgsA3 allele that encodes a defective phosphatidylglycerophosphate synthase in Escherichia coli is lethal. The only known mutations that suppress this lethality fully have been related to the major outer-membrane lipoprotein. We isolated a Bacillus subtilis chromosomal locus that suppresses the lethality when harbored in a low copy-number plasmid, without restoring...
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