INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype.

doi:10.1074/jbc.273.19.11852

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Article

INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype.

The Journal of biological chemistry - 8 May 1998

Stolz L E, Kuo W J, Longchamps J, Sekhon M K, York J D

Abstract excerpt

Sequence analysis of Saccharomyces cerevisiae chromosome IX identified a 946 amino acid open reading frame (YIL002C), designated here as INP51, that has carboxyl- and amino-terminal regions similar to mammalian inositol polyphosphate 5-phosphatases and to yeast SAC1. This two-domain primary struc...

Topics

Cold Temperature
Genes, Fungal
Homeostasis
Inositol 1,4,5-Trisphosphate
Inositol Polyphosphate 5-Phosphatases
Phenotype
Phosphatidylinositol 4,5-Diphosphate
Phosphoric Monoester Hydrolases
Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 9565610
DOI: 10.1074/jbc.273.19.11852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9565610-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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