Article
Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells.
Nature - 16 Apr 1998
Tollefson A E, Hermiston T W, Lichtenstein D L, Colle C F, Tripp R A, Dimitrov T, Toth K, Wells C E, Doherty P C, Wold W S
Abstract excerpt
DNA viruses have evolved elaborate mechanisms to overcome host antiviral defences. In adenovirus-infected cells, programmed cell death (apoptosis) induced by the cytokine tumour necrosis factor (TNF) is inhibited by several adenovirus-encoded proteins. Occupation of the cell-surface receptor Fas,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
