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Concepts in Oncolytic Adenovirus Therapy

29 Sept 2021

Abstract excerpt

Oncolytic adenovirus therapy is gaining importance as a novel treatment option for the management of various cancers. Different concepts of modification within the adenovirus vector have been identified that define the mode of action against and the interaction with the tumour. Adenoviral vectors allow for genetic manipulations that restrict tumour specificity and also the expression of specific transgenes in...

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PMID: 34638863
DOI: 10.3390/ijms221910522

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