Article
Hexokinase PII has a double cytosolic-nuclear localisation in Saccharomyces cerevisiae.
FEBS letters - 3 Apr 1998
Randez-Gil F, Herrero P, Sanz P, Prieto J A, Moreno F
Abstract excerpt
We describe here that the HXK2 gene product, isoenzyme PII of hexokinase, is located in both the nucleus and the cytoplasm of Saccharomyces cerevisiae cells. This conclusion is supported by assays of hexokinase-specific activity in isolated nuclei from wild-type and hxk1lhxk2 double mutant strains, by immunoblot experiments using anti-Hxk2 antibodies and by observation of the fluorescence distribution of a...
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