Article
High prevalence of a screening-detected, HFE-unrelated, mild idiopathic iron overload in Northern Italy.
Haematologica - 1 May 2002
Barosi Giovanni, Salvaneschi Laura, Grasso Maurizia, Martinetti Miryam, Marchetti Monia, Bodini Umberto, Reggiani Alessandro, D'Agostino Francesco, Nalli Giulio, Degiuli Alberto, De Silvestri Annalisa, Arbustini Eloisa
Abstract excerpt
BACKGROUND AND OBJECTIVES: In Italy, typical HFE mutations account for only 64% of the cases with overt hereditary hemochromatosis (HH), and a common HFE-unrelated disease was hypothesized. DESIGN AND METHODS: One thousand and fifty potential blood donors were screened by iron tests, C282Y and H63D HFE mutation analysis in a region in North Italy. Subjects with repeated fasting transferrin saturation of 45% or...
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