Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic expression of HFE mutations: a French study of 1110 unrelated iron-overloaded patients and relatives.

Gastroenterology - 1 Feb 1999

Moirand R, Jouanolle A M, Brissot P, Le Gall J Y, David V, Deugnier Y

Abstract excerpt

BACKGROUND & AIMS: Two mutations have been described in the HFE gene: C282Y and H63D. The aim of this study was to determine the phenotype of the different HFE genotypes. METHODS: Clinical symptoms and iron data were examined according to HFE genotypes in 531 unrelated patients with unexplained liver iron overload and 579 relatives of hemochromatotic patients. RESULTS: Non-C282Y +/+ patients did not markedly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Histocompatibility Antigens Class I

Share to HLA Antigens

Share to Membrane Proteins

Share to Mutation

Source

Identifiers

PMID: 9922318
DOI: 10.1016/s0016-5085(99)70134-4

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic expression of HFE mutations: a French study of 1110 unrelated iron-overloaded patients and relatives.PMID 9922318Read ↗

A genotypic study of 217 unrelated probands diagnosed as "genetic hemochromatosis" on "classical" phenotypic criteria.Semantic proximity Read ↗

Haemochromatosis and HFE gene.Semantic proximity Read ↗

[Genetic hemochromatosis and the HFE gene].Semantic proximity Read ↗

Relation between HFE mutations and mild iron-overload expression.Semantic proximity Read ↗

Prevalence and clinical significance of HFE gene mutations in patients with iron overload.Semantic proximity Read ↗

Mutant HFE genotype leads to significant iron overload in patients with liver diseases from western Romania.Semantic proximity Read ↗

Mutations in the HFE gene (C282Y, H63D, S65C) in a Brazilian populationSemantic proximity Read ↗

HFE Genotype, Ferritin Levels and Transferrin Saturation in Patients with Suspected Hereditary Hemochromatosis.Semantic proximity Read ↗

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy.Semantic proximity Read ↗

HFE gene mutation (C282Y) and phenotypic expression among a hospitalised population in a high prevalence area of haemochromatosis.Semantic proximity Read ↗

HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology.Semantic proximity Read ↗

Expression of the HFE hemochromatosis gene in a community-based population of elderly women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.