Article
Polymorphism of motilin gene in patients with Crohn's disease.
Digestive diseases and sciences - 1 Apr 1998
Annese V, Piepoli A, Andriulli A, Napolitano G, Bisceglia L, Zelante L, Gasparini P
Abstract excerpt
An increasing body of evidence supports the concept of genetic heterogeneity within inflammatory bowel disease (IBD). In this study, a polymorphism of the motilin gene, which determines an amino acid substitution in the motilin protein, has been investigated in IBD patients. Fifty patients with ulcerative colitis (UC), and 52 with Crohn's disease (CD) were investigated for anti-neutrophil cytoplasmatic antibodies...
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