Article
Increased rate of factor V Leiden mutation in patients with cerebral venous thrombosis.
Journal of neurology - 1 Mar 1998
Weih M, Vetter B, Ziemer S, Mehraein S, Valdueza J M, Koscielny J, Kulozik A E, Einhäupl K M
Abstract excerpt
We investigated the association between cerebral venous thrombosis and hereditary resistance to activated protein C (APC) in 12 consecutive German patients with non-fatal cerebral venous thrombosis and in 187 controls without a history of thrombotic disorder. Three patients (25%) had a mutation in the factor V Leiden gene against only one subject in the control group. This difference was significant (P < 0.05),...
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