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Article

Disruption of the E1 and E2 Reading Frames of HPV 16 in Cervical Carcinoma Is Associated with Poor Prognosis

1 Apr 1998

Abstract excerpt

The E1 and E2 reading frames of 158 cervical carcinoma samples containing human papillomavirus (HPV) 16 were mapped using polymerase chain reaction (PCR). The reading frames were amplified using primers spanning the entire genes. Of the analyzed samples, 23% showed no amplification with the E1 primers and 29% showed no amplification with the E2 primers. There was an overlap, but not complete identity, between the...

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PMID: 9553812
DOI: 10.1097/00004347-199804000-00009

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