Article
Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.
Archives of virology - 1 Jan 2014
Tsakogiannis D, Darmis F, Gortsilas P, Ruether I G A, Kyriakopoulou Z, Dimitriou T G, Amoutzias G, Markoulatos P
Abstract excerpt
The E1 ORF is one of the most conserved regions in the human papillomavirus (HPV) genome. The complete E1 gene of the HPV16 genome was amplified with four overlapping primer sets in 16 high-grade (CIN II, III) and 13 low-grade cervical (CIN I) intraepithelial neoplasias as well as in one cervical cancer case. Sequence analysis of the E6 and E7 genes was also carried out in the same cervical samples in order to...
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