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Article

HPV16 E2 variants correlated with radiotherapy treatment and biological significance in cervical cell carcinoma.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2018

Kahla Saloua, Hammami Samia, Kochbati Lotfi, Chanoufi Mohamed Badis, Oueslati Ridha

Abstract excerpt

Specific genetic mutations in human papillomavirus type 16 (HPV16) DNA are considered important in cervical lesion progression. This study analyzes to what extent radiotherapy treatment contributes to viral DNA mutation in cervical cell carcinomas, and the biological significance of these mutations. Serial tumor tissue, including 44 cervical cancer samples, collected before and after radiotherapy, and 52 biopsies...

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Identifiers

PMID: 30081093
DOI: 10.1016/j.meegid.2018.08.001

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