Article
Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1997
Hobbie S, Chen L M, Davis R J, Galán J E
Abstract excerpt
Central to the pathogenesis of Salmonella typhimurium is its ability to engage the host cell in a two-way biochemical interaction. As a consequence of this interaction, a dedicated protein secretion system, termed type III, is activated in these bacteria and directs the translocation of signaling...
Topics
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Nucleus
- Cells, Cultured
- Enzyme Inhibitors
- Epithelial Cells
- Humans
- Imidazoles
- Interleukin-8
- Intestines
- Mutation
- NF-kappa B
- Pyridines
- Salmonella typhimurium
- Signal Transduction
- Transcription Factor AP-1
- Transfection