Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preimplantation genetic diagnosis of inherited cancer: familial adenomatous polyposis coli.

Journal of assisted reproduction and genetics - 1 Mar 1998

Ao A, Wells D, Handyside A H, Winston R M, Delhanty J D

Abstract excerpt

PURPOSE: Our purpose was to achieve preimplantation genetic diagnosis (PGD) of the dominant cancer predisposition syndrome, familial adenomatous polyposis coli (FAPC), as an alternative to prenatal diagnosis. METHODS: The affected patient was superovulated and oocytes were retrieved and fertilized by intracytoplasmic sperm injection (ICSI). Two cells were biopsied from each embryo and the whole genome was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Primers
Share to Electrophoresis
Share to APC gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Oocytes

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 9547690
DOI: 10.1023/a:1023008921386
PMCID: PMC3454978

Genes

APC
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Preimplantation genetic diagnosis of inherited cancer: familial adenomatous polyposis coli.PMID 9547690Read ↗

Preimplantation genetic diagnosis for cancer predisposition syndromes.Semantic proximity Read ↗

Genetic and clinical characterisation of familial adenomatous polyposis: a population based study.Semantic proximity Read ↗

The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells.Semantic proximity Read ↗

Preimplantation genetic diagnosis for cancer predisposition.Semantic proximity Read ↗

Avoiding transmitting identified mutations to offspring using preimplantation genetic diagnosis.Semantic proximity Read ↗

Presymptomatic diagnosis of familial adenomatous polyposis coli.Semantic proximity Read ↗

A novel mutation of the APC (adenomatous polyposis coli) gene in a familial adenomatous polyposis (FAP) patient and presymptomatic diagnosis using PCR.Semantic proximity Read ↗

Mutation detection in exons 1-14 of the adenomatous polyposis coli gene: identification of an alternatively spliced transcript.Semantic proximity Read ↗

Familial adenomatous polyposis coli in South Africa--molecular basis and diagnosis.Semantic proximity Read ↗

Detection of 12 germ-line mutations in the adenomatous polyposis coli gene by polymerase chain reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.