Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir.

AIDS (London, England) - 26 Mar 1998

Kempf D J, Rode R A, Xu Y, Sun E, Heath-Chiozzi M E, Valdes J, Japour A J, Danner S, Boucher C, Molla A, Leonard J M

Abstract excerpt

OBJECTIVE: To determine markers that are associated with the durability of virologic response to therapy with HIV protease inhibitors in HIV-infected individuals. DESIGN: This study encompassed two retrospective analyses of the duration of virologic response to protease inhibitor therapy. The first analysis included 29 patients receiving either monotherapy or combination therapy with the protease inhibitor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Mutation

Share to Predictive Value of Tests

Share to RNA, Viral

Share to Treatment Outcome

Share to Zidovudine

Source

Identifiers

PMID: 9543434
DOI: 10.1097/00002030-199805000-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir.PMID 9543434Read ↗

Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults.Semantic proximity Read ↗

Kinetics of HIV-1 RNA and resistance-associated mutations after cessation of antiretroviral combination therapy.Semantic proximity Read ↗

Rapid decline in detectability of HIV-1 drug resistance mutations after stopping therapy.Semantic proximity Read ↗

Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype.Semantic proximity Read ↗

Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline.Semantic proximity Read ↗

PharmAdapt: a randomized prospective study to evaluate the benefit of therapeutic monitoring of protease inhibitors: 12 week results.Semantic proximity Read ↗

Long-term virological outcome and resistance mutations at virological rebound in HIV-infected adults on protease inhibitor-sparing highly active antiretroviral therapy.Semantic proximity Read ↗

3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine.Semantic proximity Read ↗

Predictive value of pharmacokinetics-adjusted phenotypic susceptibility on response to ritonavir-enhanced protease inhibitors (PIs) in human immunodeficiency virus-infected subjects failing prior PI therapy.Semantic proximity Read ↗

First HAART in HIV-infected patients with high viral load: value of HIV RNA levels at 12 weeks to predict virologic outcome.Semantic proximity Read ↗

Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response.Semantic proximity Read ↗

Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.