Article
PharmAdapt: a randomized prospective study to evaluate the benefit of therapeutic monitoring of protease inhibitors: 12 week results.
AIDS (London, England) - 22 Nov 2002
Clevenbergh Philippe, Garraffo Rodolphe, Durant Jacques, Dellamonica Pierre
Abstract excerpt
OBJECTIVE: A randomized study to evaluate the usefulness of protease inhibitor (PI) therapeutic drug monitoring (TDM) in antiretroviral-experienced HIV-infected patients. METHODS: In the control arm, treatment was modified according to genotypic resistance testing. In the TDM arm, therapy was modified on the basis of genotypic resistance testing and at week 8 according to PI plasma trough levels measured at week...
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