Article
On the distribution of k-tuple matches for sequence homology: a constant time exact calculation of the variance.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 1998
Benson G, Su X
Abstract excerpt
We study the distribution of a statistic useful in calculating the significance of the number of k-tuple matches detected in biological sequence homology algorithms. The statistic is Rn,k, the total number of heads in head runs of length k or more in a sequence of iid Bernoulli trials of length n. Calculation of the mean is straightforward. Poisson approximation formulas have been used for the variance because...
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