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Article

The oxidation of naphthalene and pyrene by cytochrome P450cam.

FEBS letters - 13 Mar 1998

England P A, Harford-Cross C F, Stevenson J A, Rouch D A, Wong L L

Abstract excerpt

Mutants of the heme monooxygenase cytochrome P450cam in which Y96 had been replaced with hydrophobic residues, have been shown to oxidise naphthalene and pyrene with rates one to two orders of magnitude faster than the wild-type. Naphthalene was oxidised to 1- and 2-naphthol, probably via the 1,2-oxide intermediate. In the case of the Y96F mutant, naphthalene was oxidised at a rate comparable to camphor. Pyrene...

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Source

Identifiers

PMID: 9539165
DOI: 10.1016/s0014-5793(98)00189-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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