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Article

Mutant Human Presenilin 1 Protects presenilin 1 Null Mouse against Embryonic Lethality and Elevates Aβ1–42/43 Expression

1 Mar 1998

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9539133
DOI: 10.1016/s0896-6273(00)80999-x

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Mutant Human Presenilin 1 Protects presenilin 1 Null Mouse against Embryonic Lethality and Elevates Aβ1–42/43 ExpressionPMID 9539133Read ↗

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Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine TissuesSemantic proximity Read ↗

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Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1and results in apoptosis and tumor suppressionSemantic proximity Read ↗

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Presenilins, processing of beta-amyloid precursor protein, and notch signaling.Semantic proximity Read ↗

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1Semantic proximity Read ↗

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