Article
Comparison of responses evoked by mild indirect cooling and by sound in the forearm vasculature in patients with homozygous sickle cell disease and in normal subjects.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society - 1 Feb 1998
Mohan J S, Marshall J M, Reid H L, Thomas P W, Hambleton I, Serjeant G R
Abstract excerpt
In normal individuals, novel or noxious stimuli commonly evoke the pattern of the alerting or defence response which includes cutaneous vasoconstriction, but vasodilatation in forearm skeletal muscle. We have compared cardiovascular responses evoked by sound and by indirect cooling in 60 patients with homozygous sickle cell (SS) disease and in 30 control subjects with normal haemoglobin genotype (AA). A sound of...
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