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Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5.

Vaccine - 24 Oct 2024

Gao Hui, Zhang Shujun, Chang He, Guo Yuxin, Li Zhonghua, Wang Yongqiang, Gao Li, Li Xiaoqi, Cao Hong, Zheng Shijun J

Abstract excerpt

Infectious bursal disease virus (IBDV) is an acute and highly infectious RNA virus known for its immunosuppressive capabilities, chiefly inflicting rapid damage to the bursa of Fabricius (BF) of chickens. Current clinical control of IBDV infection relies on vaccination. However, the emergence of novel variant IBDV (nVarIBDV) has posed a threat to the poultry industry across the globe, underscoring the great...

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Identifiers

PMID: 38944579
DOI: 10.1016/j.vaccine.2024.06.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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