Article
Genetic variation of Porphyromonas gingivalis genes encoding gingipains, cysteine proteinases with arginine or lysine specificity.
Biological chemistry - 1 Feb 1998
Mikolajczyk-Pawlinska J, Kordula T, Pavloff N, Pemberton P A, Chen W C, Travis J, Potempa J
Abstract excerpt
Porphyromonas gingivalis hemagglutinating cysteine proteinases (gingipains) are considered as important virulence factors in the development of adult periodontitis. Using Southern blot analysis it was determined that genes of three distinct but related gingipains (gingipain-R1, gingipain-R2 and g...
Topics
- Adhesins, Bacterial
- Amino Acid Sequence
- Arginine
- Base Sequence
- Binding Sites
- Cloning, Molecular
- Cysteine Endopeptidases
- DNA, Bacterial
- Genes, Bacterial
- Genetic Variation
- Gingipain Cysteine Endopeptidases
- Hemagglutinins
- Humans
- Lysine
- Molecular Sequence Data