Article
Snapback SSCP analysis: engineered conformation changes for the rapid typing of known mutations.
Human mutation - 1 Jan 1998
Wilton S D, Honeyman K, Fletcher S, Laing N G
Abstract excerpt
Several approaches may be applied to detect known mutations, including restriction enzyme cleavage, allele-specific oligonucleotide (ASO) hybridization or amplification, dideoxy fingerprinting, and direct DNA sequencing. All these approaches require several extra steps after PCR and may involve r...
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