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Article

A model for the nucleotide-binding domains of ABC transporters based on the large domain of aspartate aminotransferase.

Proteins - 15 Feb 1998

Hoedemaeker F J, Davidson A R, Rose D R

Abstract excerpt

ABC transporters are a large superfamily of integral membrane proteins involved inATP-dependent transport across biological membranes. Members of this superfamily play roles in a number of phenomena of biomedical interest, including cystic fibrosis (CFTR) and multidrug resistance (P-glycoprotein, MRP). Most ABC transporters are predicted to consist of four domains, two membrane-spanning domains and two...

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Identifiers

PMID: 9517543

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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