Article
A recombinant peptide model of the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator: comparison of wild-type and delta F508 mutant forms.
Protein science : a publication of the Protein Society - 1 Jan 1996
Yike I, Ye J, Zhang Y, Manavalan P, Gerken T A, Dearborn D G
Abstract excerpt
A series of recombinant peptides, each including the sequence proposed to be the first nucleotide-binding fold of cystic fibrosis transmembrane conductance regulator (CFTR), has been produced in an attempt to find a model peptide that would autologously fold into a soluble structure with native-like properties. The peptide NBDIF, which contains the 267-amino acid sequence of CFTR from 384 to 650, meets these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.