Article
A recombinant peptide model of the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator: comparison of wild-type and delta F508 mutant forms.
Protein science : a publication of the Protein Society - 1 Jan 1996
Yike I, Ye J, Zhang Y, Manavalan P, Gerken T A, Dearborn D G
Abstract excerpt
A series of recombinant peptides, each including the sequence proposed to be the first nucleotide-binding fold of cystic fibrosis transmembrane conductance regulator (CFTR), has been produced in an attempt to find a model peptide that would autologously fold into a soluble structure with native-l...
Topics
- Adenosine Diphosphate
- Adenosine Triphosphate
- Circular Dichroism
- Cloning, Molecular
- Cystic Fibrosis Transmembrane Conductance Regulator
- Hydrolysis
- Models, Molecular
- Mutation
- Protein Binding
- Protein Folding
- Protein Structure, Secondary
- Recombinant Proteins