Article
Cross-inhibition of both estrogen receptor alpha and beta pathways by each dominant negative mutant.
FEBS letters - 20 Feb 1998
Ogawa S, Inoue S, Orimo A, Hosoi T, Ouchi Y, Muramatsu M
Abstract excerpt
Both estrogen receptor alpha (ERalpha) and the recently identified ERbeta are nuclear receptors that are activated by estrogen. It was reported that ERalpha and ERbeta form heterodimers. Here, we show that they activate transcription independently rather than synergistically via estrogen response elements (ERE). To show the cross-talk between ERalpha and ERbeta, we utilized dominant negative mutants of ERs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
