The molecular genetics of the long QT syndrome: genes causing fainting and sudden death.

Abstract excerpt

The congenital long QT syndrome is an autosomal-dominant genetic disorder of cardiac electrical repolarization. It is caused by mutations of at least six genes, of which four, all encoding for cardiac ion channels, have been identified: KVLQT1, HERG, and Min K encode for cardiac potassium ion channels, and SCN5A encodes for the cardiac sodium ion channel. In each case the altered ion channel function produces...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Child
• Share to Chromosome Mapping
• Share to Diagnosis, Differential