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Article

Mutant AP endonuclease in patients with amyotrophic lateral sclerosis.

Neuroreport - 26 Jan 1998

Olkowski Z L

Abstract excerpt

Among the more frequent oxidative DNA injuries is the formation of abasic sites (AP sites) resulting from removal of purine or pyrimidine bases, estimated to occur at a rate of 1 x 10(4)/genome/24 h. A defect in DNA repair at this level could account for the accumulation of mutations and subseque...

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Source

Identifiers

PMID: 9507962
DOI: 10.1097/00001756-199801260-00012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9507962-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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