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Modification of topA in Synechococcus sp. PCC 7942 resulted in mutants capable of growing under low but not high concentration of CO2.

FEMS microbiology letters - 15 Feb 1998

Gabay C, Lieman-Hurwitz J, Hassidim M, Ronen-Tarazi M, Kaplan A

Abstract excerpt

Insertion of a cartridge encoding kanamycin resistance within an open reading frame, ORF839, in the cyanobacterium Synechococcus sp. PCC 7942 resulted in merodiploids bearing both the normal and the modified ORF839, suggesting that its gene product is essential for growth. In the absence of kanam...

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Carbon Dioxide
Cyanobacteria
DNA Topoisomerases, Type I
Genes, Bacterial
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9503631
DOI: 10.1111/j.1574-6968.1998.tb12881.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9503631-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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