Article
Factor VII R353Q polymorphism and lacunar stroke in Japanese hypertensive patients and normotensive controls.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Nov 1997
Nishiuma S, Kario K, Nakanishi K, Yakushijin K, Kageyama G, Matsunaka T, Matsuo T, Kanai N, Ikeda U, Shimada K, Matsuo M
Abstract excerpt
Elevated plasma factor VII (FVII) levels are reported to be associated with cardiovascular disease in both Caucasians and Japanese. Recent reports indicate that individuals with the FVII 353Q allele have decreased plasma FVII levels. Thus, we investigated the association between lacunar stroke and the FVII R353Q polymorphism in 137 hypertensive patients with silent or overt lacunar stroke (stroke group), 83...
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