The 27-bp repeat polymorphism in intron 4 of the endothelial cell nitric oxide synthase gene and ischemic stroke in a Japanese population.

doi:10.1097/00001721-199807000-00002

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Article

The 27-bp repeat polymorphism in intron 4 of the endothelial cell nitric oxide synthase gene and ischemic stroke in a Japanese population.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 1998

Yahashi Y, Kario K, Shimada K, Matsuo M

Abstract excerpt

Endothelium-derived nitric oxide formed by endothelial constitutive nitric oxide synthase (ecNOS) mediates endothelium-dependent vasodilation and antithrombotic action. We analyzed the distribution of a polymorphism of ecNOS (27-bp repeat in intron 4) in 127 ischemic stroke patients (18 with athe...

Topics

Aged
Alleles
Cerebrovascular Disorders
Female
Gene Frequency
Humans
Introns
Japan
Male
Middle Aged
Nitric Oxide Synthase
Nitric Oxide Synthase Type III
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid

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Open in PubMed

Identifiers

PMID: 9712288
DOI: 10.1097/00001721-199807000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9712288-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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