Article
R353Q polymorphism, activated factor VII, and risk of premature myocardial infarction in Japanese men.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jun 2004
Ogawa Masakazu, Abe Satoshi, Biro Sadatoshi, Saigo Masahiko, Kihara Takashi, Setoyama Shiro, Matsuoka Tatsuru, Toda Hitoshi, Torii Hiroyuki, Atsuchi Yoshihiko, Toyama Yoshifumi, Tateishi Shigeki, Minagoe Shinichi, Maruyama Ikuro, Tei Chuwa
Abstract excerpt
BACKGROUND: The association between myocardial infarction (MI) and the R353Q polymorphism of the Factor VII (FVII) gene, which reportedly influences FVII concentrations, activated Factor VII (FVIIa), or FVII antigen (FVIIag), remains controversial. METHODS AND RESULTS: The present case - control study in 127 Japanese men with their first MI at or before 45 years of age and 150 matched healthy controls was...
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