Article
Helicobacter pylori and gastric carcinogenesis.
Journal of clinical gastroenterology - 1 Jan 1997
Tsuji S, Tsujii M, Sun W H, Gunawan E S, Murata H, Kawano S, Hori M
Abstract excerpt
This article consists of three independent studies regarding Helicobacter pylori-related gastric carcinogenesis. Ammonia, a Helicobacter product, promoted chemically induced gastric carcinogenesis in animals. Moreover, an extract of Helicobacter stimulated inflammatory production of nitric oxide (NO), a potent mutagen that causes G:C-->A:T transition. Meta-analysis of recent studies demonstrated that G:C-->A:T...
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