Article
Structure, sequence, and transcriptional analysis of the Babesia bovis rap-1 multigene locus.
Molecular and biochemical parasitology - 1 Jun 1998
Suarez C E, Palmer G H, Hötzel I, McElwain T F
Abstract excerpt
The complexity of multigene families encoding rhoptry proteins and the generation of new variants in these families are constraints to development of vaccines incorporating rhoptry proteins. For example, the Babesia bigemina rhoptry associated protein (rap)-1 locus is composed of tandemly arranged genes including four polymorphic rap-1a genes and two classes of divergent genes, rap-1b and rap-1c. B. bigemina...
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