Article
Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization.
Biochemical and biophysical research communications - 4 Feb 1998
Miki H, Takenawa T
Abstract excerpt
Verprolin is a yeast protein whose inactivation leads to a cytoskeletal defect characterized by the abnormal organization of actin filaments. Recently, two mammalian proteins previously shown to regulate the actin cytoskeleton, Wiskott-Aldrich Syndrome Protein (WASP) and its homolog expressed in...
Topics
- Actins
- Amino Acid Sequence
- Animals
- Binding Sites
- COS Cells
- Cytoskeleton
- Fungal Proteins
- Microfilament Proteins
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins
- Peptide Fragments
- Protein Binding
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Wiskott-Aldrich Syndrome
- Wiskott-Aldrich Syndrome Protein, Neuronal