Article
Genetic differences between human immunodeficiency virus type 1 subpopulations in faeces and serum.
The Journal of general virology - 1 Feb 1998
van der Hoek L, Sol C J, Maas J, Lukashov V V, Kuiken C L, Goudsmit J
Abstract excerpt
To study human immunodeficiency virus type 1 (HIV-1) compartmentalization between intestine and blood, paired faecal and serum samples were collected from 204 HIV-1-infected persons. Direct sequencing of the gp120 V3 region obtained from 33 persons showed that faecal and serum sequences could be nearly homologous (0.3% different) or very dissimilar (11.3% different). Individual clones were obtained and sequenced...
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