Article
In vivo sequence changes of HIV-1 envelope V2 and V3 loops.
Leukemia - 1 Apr 1997
Shioda T, Oka S, Nagai Y
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) circulates in vivo as heterogeneous mixed populations (quasispecies). We analyzed the quasispecies nature of the first, second, and third hypervariable loops (V1, V2, and V3) of the gp 120 in plasma and viral isolates obtained from 19 infected individua...
Topics
- Cloning, Molecular
- Coculture Techniques
- HIV Envelope Protein gp120
- HIV Seronegativity
- HIV Seropositivity
- HIV-1
- Humans
- Lymphocyte Activation
- Lymphocytes
- Phenotype
- Polymerase Chain Reaction