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[Genotype and phenotype of apolipoprotein E in patients with Alzheimer's disease in Castille and Leon].

Neurologia (Barcelona, Spain) - 1 Nov 1997

Cacho J, Breñas T, González C, Arroyo T, Arcaya J, García R, Guerrero A L, Navajo J A, García C, González Buitrago J M

Abstract excerpt

We determined the variants of the apolipoprotein E (apo-E) in a sample taken from a castellano-leonesa population with Alzheimer's disease (AD). The prevalence of the allele E-4 is 0.33 in AD and 0.12 in the control group. This results allow us to estimate that the risk of suffering from the disease is higher when the patients have an allele E-4. A significant correlation was found between the presence of the...

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PMID: 9471175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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