Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene

1 Mar 1998

Abstract excerpt

Two mouse mutations gyro (Gy) and hypophosphatemia (Hyp) are mouse models for X-linked hypophosphatemic rickets and have been shown to be deleted for the 5' and 3' end of the mouse homolog of PHEX (phosphate regulating gene with homologies to endopeptidases on the X chromosome; formerly called PEX), respectively. In addition to the metabolic disorder observed in Hyp mice, male Gy mice are sterile and show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Pancreatic function and diabetes
Share to Polyamine Metabolism and Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9467015
DOI: 10.1093/hmg/7.3.541

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spermine deficiency in Gy mice caused by deletion of the spermine synthase genePMID 9467015Read ↗

Spermine synthesis is required for normal viability, growth, and fertility in the mouse.Semantic proximity Read ↗

Pex Gene Deletions in Gy and Hyp Mice Provide Mouse Models for X-Linked HypophosphatemiaSemantic proximity Read ↗

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson SyndromeSemantic proximity Read ↗

The X chromosome deletion in HYP mice extends into the intergenic region but does not include the SAT gene downstream from Phex.Semantic proximity Read ↗

Polyamine Homeostasis in Snyder-Robinson SyndromeSemantic proximity Read ↗

Genetic mapping in the Xp11.2 region of a new form of X-linked hypophosphatemic rickets.Semantic proximity Read ↗

Spermine synthase deficiency resulting in X-linked intellectual disability (Snyder-Robinson syndrome).Semantic proximity Read ↗

Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia.Semantic proximity Read ↗

Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.Semantic proximity Read ↗

Genetic screening for X-linked hypophosphatemic mice and ontogenic characterization of the defect in the renal sodium-phosphate transporter.Semantic proximity Read ↗

Blind sterile 2 (bs2), a hypomorphic mutation in Agps, results in cataracts and male sterility in mice.Semantic proximity Read ↗

Craniofacial abnormalities in mice with X-linked hypophosphatemic genes (Hyp or Gy).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.