Estrogens Increase Transcription of the Human Endothelial NO Synthase Gene

Abstract excerpt

Estrogens have been found to reduce the incidence of cardiovascular disease that has been ascribed in part to an increased expression and/or activity of the vasoprotective endothelial NO synthase (NOS III). Some reports have shown that the level of expression of this constitutive enzyme can be upregulated by estrogens. The current study investigates the molecular mechanism of the NOS III upregulation in human...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eicosanoids and Hypertension Pharmacology
• Share to Estrogen and related hormone effects
• Share to Nitric Oxide and Endothelin Effects