Article
A high-resolution genotyping method for HLA-C alleles and possible shared HLA-C-B haplotypes between Japanese and Caucasians.
Tissue antigens - 1 Dec 1997
Wang H, Tokunaga K, Ishikawa Y, Tanaka H, Kashiwase K, Shibata Y, Juji T
Abstract excerpt
A genotyping system for HLA-Cw alleles using methods of PCR-single-strand conformation polymorphism (SSCP) and PCR-sequence-specific primers (SSP) was developed. Genomic DNA from 167 random healthy Japanese individuals were investigated to determine HLA-C allele frequencies and their associations...
Topics
- Alleles
- Asian People
- Chromosome Mapping
- Gene Frequency
- Genes, MHC Class I
- Genotype
- HLA-B Antigens
- HLA-C Antigens
- Haplotypes
- Humans
- Japan
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- White People