Article
A high-resolution genotyping method for HLA-C alleles and possible shared HLA-C-B haplotypes between Japanese and Caucasians.
Tissue antigens - 1 Dec 1997
Wang H, Tokunaga K, Ishikawa Y, Tanaka H, Kashiwase K, Shibata Y, Juji T
Abstract excerpt
A genotyping system for HLA-Cw alleles using methods of PCR-single-strand conformation polymorphism (SSCP) and PCR-sequence-specific primers (SSP) was developed. Genomic DNA from 167 random healthy Japanese individuals were investigated to determine HLA-C allele frequencies and their associations with HLA-A and -B loci. Nine alleles were frequently detected: Cw*0102 (18.3%), Cw*0304 (12.0%), Cw*1202 (11.4%),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
