Article
Genotyping and association analysis of HLA-B61 in Japanese.
Human immunology - 1 Jun 1993
Lin L, Tokunaga K, Ogawa A, Ishikawa Y, Kashiwase K, Akaza T, Kuwata S, Tadokoro K, Juji T
Abstract excerpt
The distribution of HLA-B61-related alleles, B*4002-B*4006, was examined in the Japanese population by using PCR-SSO and PCR-RFLP methods. About half of the B61-positive individuals possessed B*4002 and the remaining half possessed B*4006. In addition, these two major B61 alleles were separately associated with different HLA-C alleles: B*4002 exhibited a strong linkage disequilibrium with Cw10, whereas B*4006 was...
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