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Article

Denaturation fingerprinting: two related mutation detection methods especially advantageous for high G + C regions.

BioTechniques - 1 Jan 1998

Liu Q, Weinshenker B G, Wingerchuk D M, Sommer S S

Abstract excerpt

Two versions of denaturation fingerprinting (dnF2R and dnF1R are described for detecting mutations. DnF2R is a sensitive screening method in which fingerprints are generated by performing denaturing gel electrophoresis on bidirectional "cycle-sequencing" reactions with each of two dideoxy terminators, e.g. ddATP and ddCTP. When the fingerprints generated by ddATP and ddCTP are combined, all sequence changes are...

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PMID: 9454966
DOI: 10.2144/98241rr01

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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