Transmission of the FRAXA haplotype from three nonpenetrant brothers to their affected grandsons: an update with AGG interspersion analysis.

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Article

Transmission of the FRAXA haplotype from three nonpenetrant brothers to their affected grandsons: an update with AGG interspersion analysis.

American journal of medical genetics - 6 Jan 1998

Mogk R L, Carson N L, Chudley A E, Dawson A J

Abstract excerpt

Recently, we reported on a family showing transmission of the FRAXA gene by three nonpenetrant, normally intelligent, full and half brothers to their affected grandsons [Kirkilionis et al., 1992]. We have reanalyzed this family for CGG repeat size by polymerase chain reaction (PCR) amplification/...

Topics

Adenosine
Alleles
Base Composition
Base Sequence
Chromosome Fragility
Deoxyribonucleases, Type II Site-Specific
Female
Fragile X Syndrome
Genetic Linkage
Genetic Markers
Guanosine
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Molecular Sequence Data

Pedigree

Sequence Analysis, DNA

Trinucleotide Repeats

Source

Open in PubMed

Identifiers

PMID: 9450853

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9450853-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Transmission of the FRAXA haplotype from three nonpenetrant brothers to their affected grandsons: an update with AGG interspersion analysis.PMID 9450853Read ↗

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