Article
Evidence of genetic transmission in African iron overload.
Blood - 1 Feb 1998
Moyo V M, Mandishona E, Hasstedt S J, Gangaidzo I T, Gomo Z A, Khumalo H, Saungweme T, Kiire C F, Paterson A C, Bloom P, MacPhail A P, Rouault T, Gordeuk V R
Abstract excerpt
Iron overload in Africa was previously regarded as purely due to excessive iron in traditional beer, but we recently found evidence that transferrin saturation and unsaturated iron binding capacity may be influenced by an interaction between dietary iron content and a gene distinct from any HLA-linked locus. To determine if serum ferritin follows a genetic pattern and to confirm our previous observations, we...
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