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Article

Ferroportin (Q248H) mutations in African families with dietary iron overload.

Journal of gastroenterology and hepatology - 1 Dec 2005

McNamara Lynne, Gordeuk Victor R, MacPhail A Patrick

Abstract excerpt

BACKGROUND: Dietary iron overload found in sub-Saharan Africa might be caused by an interaction between dietary iron and an iron-loading gene. Caucasian people with ferroportin gene mutations have iron overload histologically similar to that found in African patients with iron overload. Ferroportin is also implicated in the hypoferremic response to inflammation. The prevalence of the ferroportin Q248H mutation,...

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PMID: 16336444
DOI: 10.1111/j.1440-1746.2005.03930.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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