Article
Transferrin polymorphism influences iron status in blacks.
Clinical chemistry - 1 Oct 2000
Kasvosve I, Delanghe J R, Gomo Z A, Gangaidzo I T, Khumalo H, Wuyts B, Mvundura E, Saungweme T, Moyo V M, Boelaert J R, Gordeuk V R
Abstract excerpt
BACKGROUND: Genetic variants of human transferrin (TF) have been described, but little is known about their functional differences. We studied iron status according to TF phenotype in a healthy Zimbabwean population and in subjects at risk of African iron overload. METHODS: The study population consisted of 483 nondrinkers, 31 drinking spouse pairs, and 5 family pedigrees (n = 88) with index cases of iron...
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